ionstitute.org
Initiatives open-source neurobiology

Open collective. Open-source initiatives.

Initiatives 001-003
001

What wires what?

Pharmacological Extinction Neuromorphology

Modelling neural reorganization as mu-opioid blockade extinguishes endorphin-reinforced compulsion.

DRUG REPURPOSING PATIENT-FOCUSED FDA-FACING

Why it matters: mechanism-informed repurposing.

002

What reinforces what?

Neuropsychiatric Treatment Diffusion

Modelling how approved treatments diffuse through clinical networks, where graph topology reinforces or blocks use.

NETWORK SCIENCE PUBLIC BENEFIT GRAPH TOPOLOGY

Why it matters: value lost after approval.

003

What builds what?

Human Neurolipidome Inside Out

Building a system-level atlas of dynamic mother-milk lipids alongside the growing infant-brain lipidome.

OPEN ATLAS DEVELOPMENTAL DATA HARMONIZATION

Why it matters: precision in neuronutrition.